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Yuchien Chou

Yuchien Chou

Vice President at Ensigna Biosystems

San Pablo, California

Twenty plus years of hands-on research and supervisory experience in preclinical pharmacology, translational oncology and biomarker strategy for therapeutic drug discovery. Strengths include an extensive knowledge of cancer biology, endocrinology, immunohistochemistry and direct experience with in vivo models for small molecule inhibitors in oncology and metabolic diseases. Extensive experience in leading multiple projects with PK, PD, efficacy, and toxicology experiments to support lead optimization and translational research. Accomplished in project planning and execution, interfacing with cross-functional teams, managing external collaborations, CROs and meeting tight project timelines.

Specialties: In vivo pharmacology (oncology and metabolic areas), rodent pharmacokinetics, solid tumor and surrogate tissue pharmacodynamics, rodent efficacy (solid tumor, metastasis, survival), nonGLP toxicology evaluation, cell and tissue cultures (rodent and human tissue), biomarker identification and validation (rodent and human tissue).


  • Research scientist II, Pharmacology (Exelixis)
  • Vice President (Ensigna Biosystems)
  • Research scientist I, Experimental Pathology/Translational Sciences (Novartis (formerly Chiron Corporation))
  • Senior Scientist (VizaPath)
  • Consultant (Explora BioLabs)


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