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Palani Balu

Palani Balu

Principal Scientist - Leading Bioconjugation Process Development (PDM/CMC Group) at Bolt Biotherapeutics, Inc.

Cupertino, California

Principal Scientist (Bioconjugation Process Development)

Boltbody -Immune-stimulating Antibody Conjugates, Antibody Oligonucleotide Conjugate (AOC) / Antibody Drug Conjugates/ Protein Analytical Chemistry / Method Development / Antibody Purification / Bispecific Antibodies / Nanomedicines

Currently, leading Bioconjugation Process Development (PDM/CMC). Lead scientist for Antibody Oligonucleotide Conjugates (AOC) for muscle diseases. Significant contributor to Affymax’s Omontys drug development. Proven successful in introducing and implementing new methods and technologies into research and process development. Solved key obstacles in many multidisciplinary projects using scientific approaches to prioritize experiments. Co-authored a book chapter, 22 issued patents, and publication of 17 papers in premier scientific journals including Science and Nature Biotechnology. Supervised and mentored 15 scientists and associates.


  • Senior Scientist (Durect Corporation)
  • Scientist II (Chiron Corporation (Novartis Vaccines and Diagnostics))
  • Assistant Director (Avidity Biosciences, Inc.)
  • Principal Scientist - Leading Bioconjugation Process Development (PDM/CMC Group) (Bolt Biotherapeutics, Inc. )
  • Senior Principal Scientist (CovX (Pfizer BTx))


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